Scientific Subprojects
Project Area C
Biochemistry and Biophysics
The understanding of proteins and DNA including their structure and behavior is the basis for research works in many disciplines. For the reason of the complexity and dynamics of these systems and their interactions with surrounding solvents it is necessary to consider long time periods and many particles. In the SFB 716 methods for the study of biopolymers in complex environments and processes are used and further developed.
Subproject C.1
Modeling the Influence of Organic Solvents on Structure and Flexibility of Enzymes
Apl. Prof. Dr. Jürgen Pleiss
Subproject C.5
Macromolecular Transport by Nanoscaled Pores
Prof. Dr. Christian Holm
Subproject C.6
Umbrella-Sampling-Simulation
Prof. Dr. Johannes Kästner
Subproject C.8
Molecular dynamics simulations for the detection of unfolding pathways and stable conformations of DNA Gquadruplexes
Dr. Jens Smiatek, Prof. Dr. Johannes Kästner
Subproject C.9
Diamondoid-functionalized nanopores as biosensors
Jun.-Prof. Dr. Maria Fyta
Terminated Subprojects
Subproject C.3
Modelling the Inhibitor Resistance in β-Lactamases
Prof. Dr. Jürgen Pleiss
Subproject C.4
Investigating Protein Translocation Using Molecular Dynamics Simulation
Prof. Dr. Jörg Wrachtrup